The likelihood of an inadequate supply of PUFA is greatest in people whose need is increased, for example in the case of infections, chronic diseases or in growth phases. https://www.karger.com/Article/Pdf/282107
Thus, PUFAs and their metabolites have broad antimicrobial effects
ALA can act as a powerful anti-inflammatory agent for inflammation of the surface of the eye. The anti-inflammatory effects of ALA are comparable to those of corticosteroids and are mediated by NF-κB signal transduction
The results of many of the studies described here show that ALA is not only essential, but also has therapeutic properties.
Epidemiological studies and human nutrition studies suggest that alpha-linolenic acid is an important cardioprotective nutrient.